Amphotericin B Induces Glial Cell Line-Derived Neurotrophic Factor in the Rat Brain

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Amphotericin B Induces Glial Cell Line-Derived Neurotrophic Factor in the Rat Brain

Amphotericin B (AmB) is a polyene antifungal drug and is reported to be one of a few reagents having therapeutic effects on prion diseases, that is, a delay in the appearance of clinical signs and prolongation of the survival time in an animal model. In prion diseases, glial cells have been suggested to play important roles; however, the therapeutic mechanism of AmB on prion diseases remains el...

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ژورنال

عنوان ژورنال: Journal of Veterinary Medical Science

سال: 2014

ISSN: 0916-7250,1347-7439

DOI: 10.1292/jvms.14-0160